(2024)
S6K1 deficiency in tumor stroma impairs lung metastasis of melanoma in mice.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
4,
696
(2023)
The Novel Inhibitory Effect of YM976 on Adipocyte Differentiation.
CELLS.
12,
2
(2022)
Anti-Adipogenic Effects of Salicortin from the Twigs of Weeping Willow (Salix pseudolasiogyne) in 3T3-L1 Cells.
MOLECULES.
27,
20
(2022)
Bioactive Phytochemicals from Salix pseudolasiogyne Twigs: Anti-Adipogenic Effect of 2 '-O-Acetylsalicortin in 3T3-L1 Cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
23,
19
(2021)
Novel anti-adipogenic effect of CF3-allylated indole in 3T3-L1 cells.
CHEMICO-BIOLOGICAL INTERACTIONS.
352,
1
(2020)
Exosome-Mediated Differentiation of Mouse Embryonic Fibroblasts and Exocrine Cells into beta-Like Cells and the Identification of Key miRNAs for Differentiation.
BIOMEDICINES.
8,
11
(2020)
Loss of S6K1 But Not S6K2 in the Tumor Microenvironment Suppresses Tumor Growth by Attenuating Tumor Angiogenesis.
TRANSLATIONAL ONCOLOGY.
13,
4
(2018)
Trichostatin A resistance is facilitated by HIF-1α acetylation in HeLa human cervical cancer cells under normoxic conditions.
Oncotarget.
9,
2
(2017)
Site-Selective Rhodium(III)-Catalyzed C-H Amination of 7-Azaindoles with Anthranils: Synthesis and Anticancer Evaluation.
ADVANCED SYNTHESIS & CATALYSIS.
359,
20
(2017)
mTOR controls ChREBP transcriptional activity and pancreatic beta cell survival under diabetic stress.
JOURNAL OF CELL BIOLOGY.
216,
7
(2017)
Sinigrin attenuates the progression of atherosclerosis in ApoE(-/-) mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression.
CHEMICO-BIOLOGICAL INTERACTIONS.
272,
(2017)
Synovial cell death is regulated by TNF-alpha-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1 alpha.
CELL DEATH & DISEASE.
8,
(2016)
Redox-Neutral Rh(III)-Catalyzed Olefination of Carboxamides with Trifluoromethyl Allylic Carbonate.
JOURNAL OF ORGANIC CHEMISTRY.
81,
22
(2016)
Depot-specific differences in angiogenic capacity of adipose tissue in differential susceptibility to diet-induced obesity.
MOLECULAR METABOLISM.
5,
11
Publications
(2019)
의과학연구의 최신 실험기법.
성균관대학교 출판부.
Lead author
(2007)
Translational Control in Metabolic Diseases: The Role of mTOR Signaling in Obesity and Diabetes.
Cold Spring Harbor Laboratory Press.
Co-author
Patent/Intellectual Property
신규한 인돌 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 비만 예방 또는 치료용 약학적 조성물.
10-2021-0000812.
20210827.
KOREA, REPUBLIC OF
1-아미노인단 및 이의 제조방법.
10-2018-0001194.
20191011.
KOREA, REPUBLIC OF
V-ATP6VOC의 발현 또는 활성 억제제를 유효성분으로 포함하는, 식도암 예방 또는 치료용 약학적 조성물.
10-2018-0098129.
20190423.
KOREA, REPUBLIC OF
인돌 유도체를 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약학적 조성물(Pharmaceutical composition for preventing or treating diabetes comprising an indole derivative as an active ingredient).
10-1973-3510000.
20190422.
KOREA, REPUBLIC OF
신규 인돌 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약학적 조성물.
10-2018-0136227.
20190218.
KOREA, REPUBLIC OF
DSCR1-4를 이용한 제2형 당뇨병 치료제의 스크리닝 방법, 및 제2형 당뇨병 진단 또는 예후 예측용 조성물.
10-2018-0056624.
20181016.
KOREA, REPUBLIC OF
V-ATPase subunit V1E1의 단백질 발현 수준을 측정하여 식도암 환자의 생존율과 예후를 예측하는 방법.
10-2016-0036093.
20160906.
KOREA, REPUBLIC OF
ChREBP의 발현 또는 활성 억제제를 유효성분으로 포함하는 제1형 당뇨병의 예방 또는 치료용 약학적 조성물.
10-2015-0110960.
20160523.
KOREA, REPUBLIC OF
INHIBITION OF S6 KINASE ACTIVITY FOR THE TREATMENT OF INSULIN RESISTANCE.
EP20040764350.
20090805.
EU
Modulation Of S6 Kinase Activity For The Treatment Of Obestiy.
EP20030773650.
20090527.
EU
INHIBITION OF S6 KINASE ACTIVITY FOR THE TREATMENT OF INSULIN RESISTANCE.
PCT/EP2004/009368.
20050303.
UNITED STATES
MODULATION OF S6 KINASE ACTIVITY FOR THE TREATMENT OF OBESTIY.
PCT/EP2003/011554.
20040429.
UNITED STATES
Conference Paper
(2019)
Nutrient sensitive signaling in metabolic homeostasis.
KSBMB 보문학술대회.
KOREA, REPUBLIC OF
(2019)
Nutrient signaling in metabolism and diabetes.
제27차 당뇨병 연구하계 Workshop.
KOREA, REPUBLIC OF
(2016)
s6K1 in the regulation of pancreatic b ceⅡ size.
2016 Symposium on Trends in Molecular and Cellular Biology.
KOREA, REPUBLIC OF
(2016)
Clinicopathologic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma.
The 9th international symposium on AMP-activated Protein Kinase.
CHINA
(2016)
Prognostic value of Vacuolar H+-ATPase subunit V1E1 protein expression in Esophageal squamous cell carcinoma.
International Conference of the Korean Society for Molecular and Cellular Biology.
KOREA, REPUBLIC OF
(2015)
새롭게 조명되는 비만관련 물질들.
2015년 대한비만학회 제30회 춘계 연수강좌.
KOREA, REPUBLIC OF
(2014)
S6K2 and ketogenesis.
대한 내분비학회 추계 심포지.
KOREA, REPUBLIC OF
(2014)
The roles of nutrient-sensitive signaling pathways in insulin action and metabolism.
2014 International Conference on Diabetes and Metabolism.
KOREA, REPUBLIC OF
(2013)
Clinical impact and molecular function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma.
생화학분자생물학회지.
KOREA, REPUBLIC OF
(2013)
Phosphorylated mTOR is an independent prognostic factor in esophageal squamous cell carcinoma.
생화학분자생물학회지.
KOREA, REPUBLIC OF
(2010)
S6 kinase signaling in insulin resistance.
제 23차 대한당뇨병학회 춘계학술대회 (23rd Spring Congress of Korean Diabetes Association).
KOREA, REPUBLIC OF
